Tramadol Drug Interactions Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Consult your pharmacist or physician if you have questions about drug interactions with Tramadol. Missed Dose of Tramadol If you miss a dose of Tramadol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Tramadol Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include cold and clammy skin, low body temperature, slowed breathing, slowed heartbeat, drowsiness, dizziness, lightheadedness, seizures, deep sleep, and loss of consciousness.

Tramadol Precautions Do not exceed the recommended dose or take Tramadol for longer than prescribed. If you experience difficulty breathing or tightness of chest; swelling of eyelids, face, or lips; or develop a rash or hives, tell your doctor immediately. Do not take any more Tramadol unless your doctor tells you to do so. Avoid alcohol while you are using this medicine. Tramadol will add to the effects of alcohol and other depressants. Do not drive, operated machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using Ultram alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. For women: if you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Ultram during pregnancy. Tramadol is excreted in breast milk. Do not breast-feed while taking Tramadol.